The victims of the cyanide poisoning all had high levels of oxygen in their blood, but the poison was interfering with how the cells use that oxygen. That same day, paramedics found the second victim unconscious on his kitchen floor after what they thought was an apparent heart attack. Most students quickly recognize that the oxygen levels in the blood do not correspond with hypoxia as the cause of death. Unfortunately, it’s been a busy week. The whole chain grinds to a halt and no ATP can be made. Adam Janus, a postal worker in another Chicago suburb also died unexpectedly, though originally it was thought he had suffered from a heart attack.
How can you reconcile this observation with the cause of death being hypoxia? After realizing that the electron transport chain was no longer functioning, you started to suspect poisoning and ran a blood test for various poisons that you knew affected the electron transport chain. Oxygen then binds with proteins to create water. While poison is the main suspect in the case, what are other ways a person could die of hypoxia? This observation piques their interest to investigate further. What additional information would you need to determine if they are connected? It is your job to answer these questions before more deaths are reported.
During this discussion, metabolites along with their functions in cellular respiration should be written on the board as a review for students. While his family gathered to mourn their loss, his brother and sister became ill and later died.
In order to determine which component of cellular respiration is affected, students must understand where these metabolites are used or produced and what their functions are.
The medical examiner also showed the tissue samples from the heart, lungs, and liver showed massive cell death. While poison is the main suspect in the case, what are other ways a person could die of hypoxia?
Students must examine the various components of cellular respiration and the role they play in ATP production in order to determine and understand the cause of death.
The reason for the hypoxia is not always clear at the first examination. Is 13 known as an unlucky letter?
Cellular respiration case study answer key – service writer
In this interrupted, problem-based case study, students explore the purpose of cellular respiration as they play the role of medical examiner, analyzing autopsy evidence to determine the mysterious cause of death for seven people. Did God create Adam respiration, so at study one man would have the answer to speak cellular key interrupted? Most deaths were very rapid, occurring within a few hours of symptoms.
Although this case was used in a small classroom, its format could easily be adapted for use in a larger class setting.
Part 2: Chicago Cyanide Murders- A Case Study in Cellular Respiration – Biology LibreTexts
For each metabolite listed in Table 1, describe its role in cellular respiration. After realizing that the electron transport chain cgicago no longer functioning, you started to suspect poisoning and ran a blood test for various poisons that you knew affected the electron transport chain.
The first was a year-old girl. In this section, students are asked to look for any abnormalities between the autopsy results and the cause of death. Respidation understand, we need to take a very close look at the structure of the mitochondrion.
If poison is suspected in the deaths, how would you proceed with the investigation? It is an interrupted case study, where students are given sequential portions of the case to analyze. Are they substrates or products?
Part IV provides students with information about cyanide poisoning and asks them to determine why this led to the deaths of the patients. Have you ever thought about why oxygen is so important?
Cyanide is an extremely fast acting poison. In your opinion, are the seven deaths connected? vellular
Part 2: Chicago Cyanide Murders- A Case Study in Cellular Respiration
Given what you know about ATP and cellular respiration, explain why cyanide is so fast acting. Since the Chicago Tylenol murders, drug companies have drastically changed how medicines are packaged. While there were cellulxr suspects, no one chucago ever charged with the crime and it is still an ongoing investigation.
Students are asked to relate this information to their knowledge of the steps of cellular respiration to determine which stage has been affected.
JCST – May/June 2014
This case has four sections, or parts. Students mueders in small groups for approximately 15 minutes, followed by 15 minutes of whole-class discussion. Student groups discuss answers to the questions for approximately minutes before another whole class discussion.
The case was developed for use in an introductory biology course taken by both science majors and nonmajors. An ambulance rushed the girl to a nearby hospital, where she was pronounced dead. Sadly, the victim’s brother and fiancee also collapsed later that night while the family gathered to mourn his passing. In the days that followed, three more unexplained deaths occurred in nearby Chicago mruders.